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Sibutramine, formerly sold under the brand name Meridia among others, is an appetite suppressant which has been discontinued in many countries.
USES OF SIBUTRAMINE:
Psychiatric conditions as bulimia nervosa, anorexia nervosa, serious depression or pre-existing mania
Patients with a history of or a predisposition to drug or alcohol abuse
Hypersensitivity to the drug or any of the inactive ingredients
Patients below 18 and above 65 years of age
Concomitant treatment with an MAO inhibitor, antidepressant or other centrally active drugs, particularly other anoretics
History of peripheral arterial disease
Hypertension that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension
Existing pulmonary hypertension
Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction
A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial
occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack (TIA))
Stroke or transient ischemic attack (TIA)
Hyperthyroidism (overactive thyroid gland)
Closed-angle glaucoma
Seizure disorders
Enlargement of the prostate gland with urinary retention (relative contraindication)
Pheochromocytoma
Pregnant and lactating women (relative contraindication). online.
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